Ng NYY, et al. - Researchers here investigated if the combination of regional tissue oxygen saturation (StO₂) measurement using near-infrared spectroscopy (NIRS), inferior vena cava collapsibility and ejection fraction (EF) is able to detect occult sepsis. It was noted that among patients with infection, change in StO₂ and time taken to reach new StO₂ baseline, combined with EF could potentially predict sepsis.