Tavasoli S, et al. - Given the numerous roles of magnesium in human’s body, such as, it acts as a protective factor in stone formation by binding to oxalate in the intestinal and urinary system, and decreasing its absorption and crystallization, respectively, researchers sought to clarify the association between the 24-h urine magnesium and other urine metabolites. In this retrospective cross-sectional study, they assessed data from 24-h urinalysis of the calcium stone-forming (CSF) patients and determined the correlation between 24-h urine (24-U) magnesium to creatinine ratio (Mg/Cr) with other 24-U metabolites to creatinine ratio, using Spearman correlation test. As per multivariate regression analysis, the higher quartile of 24-U oxalate (> 47 mg/24 h) increased the odds of 24-U magnesium more than 75 mg/24 h (data median) comparing with the lower quartile of 24-U oxalate (≤ 26 mg/24 h). As a routine diet containing rich sources of magnesium contain a high amount of oxalate as well, magnesium level in 24-h urinalysis demonstrates an obvious direct association with 24-h urine oxalate.