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ETV6-NTRK3 and STRN-ALK kinases fusions are recurrent events in papillary thyroid cancer of adult population

European Journal of Endocrinology Nov 01, 2017

Bastos AU, et al. - The purpose of this study is to determine whether ETV6-NTRK3 and STRN-ALK kinases fusions are recurrent events in papillary thyroid cancer. The identification of kinases fusions in thyroid carcinomas helps to expand their knowledge about the landscape of oncogenic alterations in PTC. As ETV6-NTRK3 and STRN-ALK are recurrent and not identified in benign lesions, they can certainly help with the diagnosis of thyroid nodules. To characterize if they can also be valuable for prognosis and guiding therapy, further analysis is needed.
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