Zhang P, et al. - Whether ethanol locks are efficacious in preventing catheter-related bloodstream infection (CRBI), was determined using data from relevant studies identified from electronic databases, including PubMed, Web of Science, Embase, and the Cochrane Library (until April 2018). Researchers also performed subgroup analysis according to the study quality, duration of the ethanol lock, disease type and CRBI definition. They applied Eggs’ method to detect publication bias and checked the stability of the meta-analysis results by performing sensitivity analysis. Based on the findings from 10 randomized controlled trials (RCTs) involving 2760 patients, they concluded that an ethanol lock may play a role in the prevention of CRBI, particularly in immunocompromised patients with hematological diseases.