Taft TH, Carlson DA, Simons M, et al. - Esophageal hypervigilance and symptom-specific anxiety are emerging as important considerations in understanding symptom reporting. As such, researchers intended to perform the first study of these constructs in eosinophilic esophagitis (EoE). Researchers conducted a retrospective review of an EoE patient registry including eosinophils per high power field, endoscopic reference score, distal distensibility plateau, Brief Esophageal Dysphagia Questionnaire, Visual Dysphagia Question of EoE Activity Index, Northwestern Esophageal Quality of Life scale, Esophageal Hypervigilance and Anxiety Scale. In this analysis, 103 individuals had complete data: 69.9% male, average age of 40.66 years. In EoE, hypervigilance and symptom-specific anxiety are important for our understanding of self-reported patient outcomes. The data implies that these processes outweigh endoscopic and histologic markers of EoE disease activity across dysphagia, difficulty eating, and HRQoL. It has been considered that clinicians should assess hypervigilance and anxiety, especially in individuals with refractory symptoms and poor HRQoL.