Chen HJ, et al. - In this cross-sectional study of non-pregnant healthy adults (aged ≥ 19 years), investigators studied the relationship between macronutrient intake at different times of the day and blood lipid levels. They assessed fasting plasma triglyceride, total cholesterol, and high-density lipoprotein (HDL) cholesterol levels in 1,283 study participants. They observed a decline in low-density lipoprotein (LDL) cholesterol by 1.46 and 1.27 mg/dL while transferring 100 kcal intake at night to the morning or noon, respectively. They also noted an association between transferring 100 kcal of fat intake at night to earlier periods and a lower LDL cholesterol level, especially transferring to noontime (significantly lower by 5.21 mg/dL) and evening (significantly lower by 3.19 mg/dL). They concluded a positive relation of nighttime energy and fat intake with raised total and LDL cholesterol levels.