Holmberg D, et al. - In this nationwide cohort study, researchers investigated if survival in esophageal adenocarcinoma (EAC) is influenced by gastroesophageal reflux disease (GERD) or endoscopy practice. Participants were all Swedish residents (n = 6,600) (79.3% males, median age 70 years) who received a diagnosis of EAC in 1997-2013 and were followed till 2018. History of GERD and endoscopies before EAC were the exposures. EAC-specific 5-year mortality was assessed as the main outcome. Findings revealed a possible association of GERD with a better prognosis in the event of EAC. However, the limited influence of the use of endoscopy screening on survival was reported unless performed very frequently.