Yoon SB, Moon SH, Song TJ, et al. - In this systematic review and comparative meta‐analysis, researchers sought to compare endoscopic ultrasound‐guided fine needle aspiration (FNA) vs fine needle biopsy (FNB) in the diagnosis of autoimmune pancreatitis (AIP). The PubMed, EMBASE, and Ovid MEDLINE databases until April 2020 were used for a comprehensive literature search. Between FNA and FNB, pooled rates of diagnostic yield for the histologic criteria of AIP, histologic tissue procurement, and adverse events were contrasted, and diagnostic yields were compared between 19‐gauge (G) and 22G needles. This meta‐analysis involved 9 studies with 309 patients who had AIP who underwent FNA and 7 studies covering 131 patients who underwent FNB. Data reported that the pooled diagnostic yields for level 1 or 2 histology criteria of AIP were 55.8% for FNA and 87.2% for FNB and the pooled histologic procurement rates for FNA and FNB were 91.3% and 87.0%. Despite the similar rate of histologic tissue procurement, the diagnostic yield may be better with FNB needles than with FNA needles for the diagnosis of AIP. A quantitative definition of the AIP histological sample may be warranted. The diagnostic yield was better with a 19G needle than with a 22G needle.