Soares WE, Melnick ER, Nath B, et al. - During the novel coronavirus 19 (COVID-19), there appeared a higher vulnerability of people with opioid use disorder (OUD) to face disruptions in access to addiction treatment and social support, which led researchers to determine the extent and subsequent changes in emergency department (ED) utilization following a nonfatal opioid overdose during COVID-19. Among adult visits to 25 EDs in Alabama, Colorado, Connecticut, North Carolina, Massachusetts, and Rhode Island from January 2018 to December 2020, they retrospectively identified opioid overdoses. Observations revealed an increase in overdose visit counts by 10.5% (N = 3,486) in 2020 compared with 2018-2019 (N = 3,020 and 3,285, respectively) despite a 14% decline in all-cause ED visits. This suggests a widespread worsening in opioid-related complications during COVID-19. Findings emphasize the necessity for expanded community and hospital-based interventions to support people with OUD and save lives during COVID-19.