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Chlamydia trachomatis and Mycoplasma genitalium prevalence and associated factors among women presenting to a pregnancy termination and contraception clinic, 2009-2019

Sexually Transmitted Infections Apr 01, 2021

Shilling HS, Garland SM, Costa AM, et al. - Researchers herein investigated the prevalence of Chlamydia trachomatis and Mycoplasma genitalium and their associated factors among women presenting to a pregnancy termination and contraception service over 10 years. They conducted retrospective analysis of clinical data obtained from 17,573 women aged 15–45 years in 2009–2019 and for 266 M. genitalium positive women tested for macrolide resistance-associated mutations in 2016–2019 and identified C. trachomatis and M. genitalium prevalence of 3.7% and 3.4%, respectively. Multivariable analyses revealed the following as shared risk factors: younger age, socioeconomic disadvantage and coinfection, with 10.1% of C. trachomatis positive women also positive for M. genitalium. For C. trachomatis and M. genitalium, additional risk factors were earlier year of visit and residing outside a major city, respectively. Observations revealed a high level of antimicrobial resistance and the prevalence of coinfection, hence they suggest that consideration could be given to testing C. trachomatis positive women for M. genitalium in this setting to prevent further spread of resistant infections.

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