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Elevated neutrophil-to-lymphocyte ratio can predict procedural adverse events in patients with ST-elevation myocardial infarction undergoing primary percutaneous coronary intervention

Coronary Artery Disease Jan 08, 2019

Machado P, et al. - In this study performed on consecutive patients with ST-segment elevation myocardial infarction (STEMI) who underwent primary percutaneous coronary intervention (PCI), researchers investigated the utility of neutrophil-to-lymphocyte ratio (NLR) in predicting procedural adverse events. Participants included 664 patients with a mean age of 60.5 (±12.1) years; 66.3% were male. These subjects were divided into low and high NLR, with high defined as an NLR value above 75° percentile (≥9.45). In this patient populace, high NLR was found to independently predict distal embolization, no-reflow, and procedural complications. The area under the curve for distal embolization, for no-reflow and for procedural complications was 0.67, 0.64, and 0.62, respectively. An excellent negative predictive value of 97.8, 96.9, and 92.1 for distal embolization, no-reflow, and procedural complications, respectively, was displayed by a low value of NLR. Overall, NLR could be a valuable and inexpensive bedside tool.

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