Vecht L, et al. - This matched case–control study examined if elevated factor VIII (FVIII) served as a risk factor for cerebral venous thrombosis (CVT), as it does for for leg-vein thrombosis. Researchers analyzed cases admitted between July 2006 and December 2016. The controls were healthy hospital staff matched for age (within 5 years) and sex. It was reported that the median time between CVT diagnosis and blood collection was 18 months. CVT cases frequently displayed elevated FVIII vs controls. Findings revealed that elevated FVIII was linked to a 15-fold increased risk of CVT. Yielded data showed that the occurrence of elevated FVIII was frequent in patients with CVT and it served as a strong risk factor for this condition.