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Elevated depressive symptoms and the risk of stroke among the Mexican older population

Journal of the American Geriatrics Society Dec 14, 2020

Meza E, Eng CW, Sáenz JL, et al. - Researchers examined links between baseline and short‐term (2‐year) alterations in increased depressive symptoms with incident self‐reported or next‐of‐kin reported doctor‐diagnosed stroke among 10,693 Mexican adults aged 50 and older with no history of prior stroke. In this prospective cohort study, a moderately higher risk of incident stroke was noted in people with elevated baseline depressive symptoms vs those without elevated baseline depressive symptoms. In analyses of short‐term alterations in increased depressive symptoms, a greater risk of incident stroke was observed in participants with recent‐onset or stable high elevated depressive symptoms vs those with stable low/no depressive symptoms, while there was no link of recently remitted symptoms with stroke hazard. Based on these data, experts inferred that strategies to decrease depressive symptoms merit assessment as approaches to avert stroke in middle‐income countries. Although the results are similar to those in high‐income countries but should be reproduced in other low‐ and middle‐income countries.

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