Singh V, et al. - Researchers compared the efficacy of standard medical therapy with pentoxifylline to treatment with a combination of granulocyte colony stimulating factor (GCSF) and standard medical therapy as well as to the combination of N-acetyl cysteine (NAC), GCSF, and standard medical therapy in patients with severe alcoholic hepatitis (AH). Compared to standard therapy, administration of GCSF was found to improve liver function and increase survival times in patients with severe AH. No evidence was found regarding the benefit of adding NAC to GCSF.