Ramezani F, et al. - In this clinical trial, researchers determined the efficacy of bladder irrigation with normal saline solution in preventing catheter-associated urinary tract infections (CAUTI) in comatose patients admitted to intensive care units. They performed randomization of eligible patients to the experimental group receiving daily bladder irrigation with 450cc sterile normal saline, in 3 150-mL doses, for 3 consecutive days or to control group. Outcomes suggested daily bladder irrigation with normal saline during 3 days as effective in preventing CAUTI in comatose patients.