Figuero E, et al. - In this network meta-analysis (NMA), researchers compared the effectiveness of various oral hygiene products for chemical biofilm control, in 6-month home-use, randomized clinical trials (RCTs), in terms of changes in the gingival index (GI). Using Löe & Silness GI, modified GI and gingival severity index, NMA protocols were applied to assess direct and indirect comparisons among products. The trial included 53 papers, 21 studies for mouth rinses and 34 for dentifrices. Findings revealed significant differences when comparing placebo vs some active agents. It was observed while comparing among active agents, no differences were found for dentifrices, while the greatest effect on GI score was showed by mouth rinses containing essential oils.