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Efficacy of a novel personalised aflibercept monotherapy regimen based on polypoidal lesion closure in participants with polypoidal choroidal vasculopathy

British Journal of Ophthalmology Feb 16, 2021

Teo KYC, Jordan-Yu JM, Tan ACS, et al. - Researchers conducted a 52-week, randomized, open-label, non-inferiority, single-centre study including 53 participants with symptomatic polypoidal choroidal vasculopathy (PCV) with the aim to compare the efficacy of aflibercept using a personalised vs fixed regimen in these patients. Per outcomes, non-inferior best-corrected visual acuity gain and numerically higher polypoidal lesions closure were achieved with personalised regimen when compared with fixed regimen.

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