Sayasone S, et al. - In participants with O viverrini infection, the efficacy and safety of a single, oral dose of tribendimidine were compared with praziquantel administered in two doses. Observations revealed that compared to praziquantel, tribendimidine had a slightly lower cure rate and was not non-inferior. However, tribendimidine showed a similar egg reduction rate to praziquantel and resulted in fewer adverse events. Thereby suggesting that it might complement praziquantel in O viverrini control programmes, particularly in settings co-endemic for hookworm.