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Efficacy and safety of tocilizumab in patients with refractory Takayasu arteritis: Results from a randomised, double-blind, placebo-controlled, phase 3 trial in Japan (the TAKT study)

Annals of Rheumatic Diseases Mar 10, 2018

Nakaoka Y, et al. - Herein, the effectiveness and safety of the interleukin-6 receptor antibody tocilizumab were assessed in subjects with Takayasu arteritis (TAK). Although the primary endpoint ie, time to relapse of TAK was not met, findings suggested favour for tocilizumab over placebo for time to relapse of TAK without new safety concerns.
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