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Effects of exercise on gait and motor imagery in people with Parkinson disease and freezing of gait

Parkinsonism & Related Disorders May 16, 2018

Myers PS, et al. - Researchers investigated impacts of exercise on gait performance, neural correlates related to these effects, and potential neural activation differences between freezers and non-freezers during motor imagery (MI) of gait. Before and after a 12-week exercise intervention, thirty-seven members from a larger exercise intervention completed behavioral assessments and functional magnetic resonance imaging (fMRI) scans. They reported that the exercise intervention had no effect while all members had significantly slower and shorter backward velocity and stride length respectively. Blood oxygen-level dependent (BOLD) signal during MI did not change with exercise; though, freezers had significantly lower BOLD signal during MI of backward (IMG-BWD) than non-freezers. This recommended potential decreased recruitment of the somatomotor network (SMN) during MI of gait in freezers.
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