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Effects of deep vs moderate neuromuscular block on the quality of recovery after robotic gastrectomy

Acta Anaesthesiologica Scandinavica Mar 01, 2019

Kim HJ, et al. - In this prospective, double-blind, single-center randomized controlled superiority trial with two parallel groups, researchers assessed the quality of postoperative recovery in relation to deep neuromuscular blockade vs moderate neuromuscular blockade in 56 adult patients (19-80 years) scheduled for elective robotic gastrectomy. In a 1:1 ratio, patients were randomized to a moderate neuromuscular blockade group or a deep neuromuscular blockade group. They mainly assessed the Quality of Recovery-40 (QoR-40) score on postoperative day 1 (primary outcome). They also evaluated the QoR-40 score on postoperative day 2, intraoperative hemodynamic data, intraoperative respiratory data, visual analog scale score for pain, postoperative incidences of nausea and vomiting, postoperative rescue analgesic use, and postoperative rescue antiemetic use (secondary outcomes). In both the groups, similar quality of postoperative recovery was observed. This implies that during robotic gastrectomy, deep neuromuscular blockade may be unnecessary, at least in patients with normal body mass index.
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