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Effects of anesthetics on postoperative 3‐month neuroendocrine function after endoscopic transsphenoidal non‐functional pituitary adenoma surgery

Acta Anaesthesiologica Scandinavica Jun 12, 2020

Oh H, Yhim HB, Yoon HK, et al. - In this study with patients undergoing endoscopic transsphenoidal surgery for removal of non‐functional pituitary adenomas, a comparison was performed between sevoflurane and propofol anesthesia in terms of 3‐month post‐operative neuroendocrine functional outcomes. This study included 356 patients. Employing propensity score matching, 3‐month post‐operative neuroendocrine functional outcomes were compared between patients who received sevoflurane‐remifentanil anesthesia (sevoflurane group) vs those given propofol‐remifentanil anesthesia (propofol group). Findings revealed that similar effects on post‐operative 3‐month neuroendocrine functional outcomes were exerted by both sevoflurane‐remifentanil and propofol‐remifentanil anesthetic techniques in this patient population. This implies that such patients can be freely administered propofol and sevoflurane in terms of post‐operative intermediate‐term neuroendocrine functional outcome.

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