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Effects of 6-month treatment with the glucagon like peptide-1 analogue liraglutide on arterial stiffness, left ventricular myocardial deformation and oxidative stress in subjects with newly diagnosed type 2 diabetes

Cardiovascular Diabetology Jan 12, 2018

Lambadiari V, et al. - This study was designed to determine the impact of 6-month treatment with the glucagon-like peptide 1 (GLP-1) analogue liraglutide on arterial stiffness and left ventricular (LV) myocardial deformation in subjects with newly diagnosed type 2 diabetes mellitus (T2DM). As a result of treating newly diagnosed T2DM patients with liraglutide for 6 months, improved arterial stiffness, LV myocardial strain, LV twisting and untwisting and amino-terminal Pro-B-Type Natriuretic Peptide (NT-proBNP), due to reduced oxidative stress, were noted.
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