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Effective use of weight-based enoxaparin for deep vein thrombosis chemoprophylaxis in patients with traumatic brain injury

American Journal of Surgery Aug 01, 2021

Taylor A, Martinez-Quinones P, Huang E, et al. - Since enoxaparin is the recommended agent for chemoprophylaxis of deep vein thrombosis in trauma patients, researchers conducted this retrospective analysis to analyze the use of weight-based enoxaparin in the setting of traumatic brain injury (TBI). Adult trauma patients admitted were studied between January 1, 2018, and February 28, 2019. Inclusion criteria were met by 66 patients with TBI who were receiving weight-based enoxaparin. When compared with other studies, the use of weight-based enoxaparin dosing in the setting of TBI shows promise without an increased incidence of intracranial hemorrhage (ICH) expansion. There were no deaths as a result of ICH expansion or venous thromboembolism.

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