Effect of two post-surgical cleansing protocols on early periodontal wound healing and cytokine levels following osseous resective surgery: A randomized controlled study
International Journal of Dental Hygiene Apr 17, 2019
Sijari Z, et al. - Researchers estimated the consequence of 2 post-surgical cleansing protocols on early periodontal wound healing and cytokine levels after osseous resective surgery in this randomized controlled study among 30 candidates. They categorized subjects into 2 groups: the test protocol (n = 15) instructed to brush the surgical area with a sonic toothbrush starting the day after surgery plus 0.12% chlorhexidine (CHX) rinsing, and the control protocol (n = 15) rinsed only with 0.12% CHX solution and resumed mechanical cleansing with a manual toothbrush on day 14 following surgery. When compared to the control group, they observed lower early wound healing scores, higher bacterial plaque reduction, and milder inflammatory response at the surgical sites in the test group on day 7, 14 and 28. A statistically significant reduction in interleukin (IL)-1β and IL-8 levels on day 14 in the sonic group accentuated the wound healing process faster.
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