Pilo R, et al. - Researchers conducted an inspection of the roughness, structure and bond strength with zirconia of four grit-blasting therapies combined with three silane types, along with an analysis of the reactivity of silanes. Great variations were illustrated by the reactivity of the silanes used, in order to support a predictable effect in all treatments. It was observed that Clearfil Ceramic Primer Plus (CP) with deactivated silanols illustrated, a) despite the lowest Sa,Sz substrate values, the most reliable and strongest therapy with a silica-rich powder (COJ) and b) high strength with a low-silica powder (SLJ) with higher Sa,Sz substrate values. Hence, 10-MDP was revealed to contribute to the bonding mechanism of the silane-containing primers to a greater extent.