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Effect of primary occlusion therapy in asymmetric, bilateral amblyopia

American Journal of Ophthalmology Nov 19, 2019

Shoshany TN, et al. - Since many bilateral amblyopia individuals have asymmetric visual acuity (VA) and there is no standard treatment for these individuals, and outcomes have not been well-described, researchers conducted this retrospective interventional comparative case series to compare VA outcomes in this group based on the timing of occlusion therapy. Study participants included patients diagnosed with amblyopia at Boston Children’s Hospital between 2010-2014. Of 2,200 individuals analyzed, 167 had asymmetric, bilateral amblyopia; 98 met inclusion and exclusion criteria. Participants were equally divided between primary (n = 50) and secondary (n = 48) occlusion groups. The authors discovered that VA improved by 4 lines in the weaker eye and 2 lines in the stronger eye in patients with asymmetric, bilateral amblyopia, on the other hand, IOD improved by 2 lines, regardless of occlusion status. Therefore, primary occlusion did not provide any additional benefit over spectacle correction alone.
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