Effect of phosphate-specific diet therapy on phosphate levels in adults undergoing maintenance hemodialysis: A systematic review and meta-analysis
Clinical Journal of the American Society of Nephrology Jan 11, 2021
St-Jules DE, Rozga MR, Handu D, et al. - Given that patients on maintenance hemodialysis develop hyperphosphatemia, and are helped by dietitians, in some dialysis centers, to manage their serum phosphate, but in view of the regularity of hyperphosphatemia in this population and constraints on kidney dietitian time, researchers assessed the evidence for this practice by performing this systematic review and meta-analysis. They explored multiple databases to identify controlled trials that assessed the impact of phosphate-specific diet therapy offered by a dietitian on serum phosphate in patients on hemodialysis. They observed a significant reduction in serum phosphate in correlation with monthly diet therapy (20–30 minutes) in patients with persistent hyperphosphatemia for 4–6 months, without compromise of nutrition status, however, this treatment strategy seemed unlikely to maintain these impacts if discontinued. Overall, experts found low-quality evidence that monthly diet therapy provided by a dietitian seems to afford a safe as well as efficacious treatment option for persistent hyperphosphatemia in patients receiving HD.
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