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Effect of different hepatitis B infection status on the prognosis of active lupus nephritis treated with immunosuppression: A retrospective analysis of 177 patients

International Journal of Rheumatic Diseases May 31, 2018

Fang J, et al. - Experts assessed if different hepatitis B virus (HBV) infection status influenced the prognosis of patients with lupus nephritis (LN) under immunosuppressive therapy. The composite renal outcome was defined as a composite of progression to end-stage renal disease, 50% estimated glomerular filtration rate decrease, or death. As per the data, for patients with active LN, a worse prognosis could be conferred with HBV infection status. Active HBV carrier, cycle of immunosuppression > 1, and delayed immunosuppressive therapy were the 3 risk factors of the composite renal outcome.
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