Ozkul C, et al. - In this study, serum concentrations of suppressors of cytokine signaling (SOCS)1, SOCS3, and brain-derived neurotrophic factor (BDNF) were assessed subsequent to an 8-week combined exercise training in MS patients and healthy individuals. Furthermore, the impacts of combined exercise training on balance, functional exercise capacity, and fatigue in patients with MS was also assessed herein. Researchers noted improved BDNF, and physical performance was noted in MS patients who received the combined exercise training. But, future studies are needed to clarify the role of SOCS proteins in MS pathogenesis and the effect of exercise on SOCS.