Kawazoe M, Funakoshi S, Ishida S, et al. - Findings demonstrate serum uric acid (SUA) level as an independent risk factor for new-onset hypertension; this tendency was significantly stronger in participants suffering from chronic kidney disease (CKD).

• A total of 3,037 individuals from the general Japanese population were included and split into four groups by quartiles of SUA level at baseline.

• They were followed for a mean span of 4.4 years, during which hypertension occurred in 943 participants.

• Relative to the reference group (the first quartile group), the calculated multivariable-adjusted hazard ratios for new-onset hypertension were 1.11 in the second quartile, 1.25 in the third quartile, and 1.35 in the fourth quartile.

• In those with CKD vs those without, the link between SUA and hypertension was significantly stronger.