Groddeck S, et al. – This study determined the impact of contamination of tooth cavities by hemostatic agents applied after blood contamination on marginal adaptation of composite restorations bonded with etch–and–rinse and self–etch adhesives. The findings suggested that cavity contamination with hemostatic agents, applied after blood contamination and removed with water spray, does not compromise marginal adaptation in enamel and dentin. However, in the case of contamination by an aluminum–chloride hemostatic agent, the tested etch–and–rinse approach resulted in a higher percentage of continuous enamel margins of composite restorations than did the self–etch approach.