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Effect of beta-blocker therapy on early mortality after emergency colonic cancer surgery

British Journal of Surgery Feb 22, 2019

Ahl R, et al. – In this cohort study that involved 3,187 adults who required emergency colonic cancer surgery between 2011 and 2016, researchers evaluated whether regular preoperative beta-blockade reduced mortality post-surgery. In all, 685 patients used regular beta-blocker therapy before surgery. The investigators found that the overall 30-day mortality rate was significantly reduced in those who received beta-blockers. In multivariable analysis of 30-day all-cause mortality, beta-blocker therapy was identified to be the only modifiable protective factor that was associated with a significant reduction in death of cardiovascular, respiratory, sepsis and multiple organ failure origin.

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