Effect of behavioral and pelvic floor muscle therapy combined with surgery vs surgery alone on incontinence symptoms among women with mixed urinary incontinence: The ESTEEM randomized clinical trial
JAMA Sep 23, 2019
Sung VW, et al. - Researchers investigated the efficacy of combining behavioral and pelvic floor muscle therapy with mid-urethral sling vs sling alone in annihilating mixed urinary incontinence symptoms. They conducted randomized clinical trial involving 480 women across 9 sites in the United States. The combined therapy group showed a decrease in incontinence symptoms (measured by the Urogenital Distress Inventory Long Form; range, 0-300 points; minimal clinically important difference, 35 points) by 128.2 points and the surgery alone group showed a decrease by 114.7 points. This suggests that behavioral and pelvic floor muscle therapy combined with mid-urethral sling surgery vs surgery alone resulted in a small statistically significant difference in urinary incontinence symptoms at 12 months that did not meet the threshold for clinical importance.
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