Fa-Binefa M, et al. - Researchers analyzed data from nearly 4,500 current or former smokers (aged 25-79 years) to investigate the potential link between an early smoking onset age (SOA) and the risk of fatal and non-fatal CVD and all-cause and CVD mortality. They also explored the linear and non-linear link between SOA and the outcomes of interest. In the link between SOA and CVD outcomes, a significant non-linear component was found with a cut-off point at 12 years; there was an inverse association of each year of delay in SOA with CVD risk and CVD mortality in the group aged ≤ 12 years. Findings revealed a linear link between SOA and all-cause mortality, and a 4% lower risk of mortality was observed in relation to each year of delay. Overall, the significance of preventing tobacco use among teenagers and adolescents was strengthened by findings.