Levin TR, Jensen CD, Chawla NM, et al. - For African Americans, some recommendations suggest beginning colorectal cancer (CRC) screening before age 50, however data on screening uptake and results in this population are scant, so researchers compared screening uptake, colonoscopy follow-up of abnormal test results, and test yield among age and racial groups in this prospective study. Fecal immunochemical test (FIT) screening among African American members of the Kaiser Permanente Northern California health plan in 2018 when they were 45–50 years old (early screening group) was compared with data from 51–56 year old African American, White, Hispanic, and Asian/Pacific Islander health plan members who were previously unscreened. Screening was completed by 33.1% of the 10,232 African Americans in the early screening group who were mailed a FIT. Proportions of African Americans who took part in early (age 45–50 years) FIT screening and test yield were similar to those of 51–56 years old African Americans, whites, Hispanics, and Asian/Pacific islanders who had previously been unscreened. Positive results from the FIT did not differ significantly among the groups; after a positive test result, more than 74% received a follow-up colonoscopy. Test yields were similar across the groups for any adenoma, advanced adenoma, and CRC.