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Early onset neutropenia and thrombocytopenia following rituximab in lupus nephritis

International Journal of Rheumatic Diseases Feb 01, 2019

Shah S, et al. - Researchers assessed the data to estimate the importance of recognizing early onset cytopenia following rituximab (a monoclonal antibody against CD20 receptor ) in lupus nephritis. They noticed cytopenia including neutropenia as a late event (>4 weeks) in some cases. But a few cases of early-onset neutropenia (EON) and thrombocytopenia were also observed in the literature. They noted a good response of neutropenia to granulocyte colony-stimulating factor treatment and thus recovered the platelets spontaneously.
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