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Early intervention for the treatment of acute laryngeal injury after intubation

JAMA Otolaryngology-Head & Neck Surgery Mar 19, 2021

Lowery AS, Malenke JA, Bolduan AJ, et al. - Researchers conducted this retrospective cohort study for comparing functional outcomes between early and late intervention for intubation-related laryngeal injury. The sample consisted of 29 patients with a laryngeal injury resulting from endotracheal intubation who were assessed at a tertiary care center between May 1, 2014, and June 1, 2018. When compared to late intervention, defined as an intervention performed greater than 45 days after intubation, early intervention, defined as a procedure performed 45 days or less after intubation, for patients with postintubation laryngeal injury was associated with a shorter duration of tracheostomy dependence, a higher rate of decannulation, and fewer surgical procedures. Patients who received early intervention avoided open reconstruction as well. Such findings may have implications for the management of patients who require prolonged periods of endotracheal intubation during recovery from severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection.

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