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Early colonoscopy for diverticular bleeding does not reduce risk of postdischarge recurrent bleeding: A propensity score matching analysis

Clinical Gastroenterology and Hepatology Apr 25, 2019

Nigam N, et al. - Using Marketscan (Truven Health Analytics, Inc, Ann Arbor, MI), a nationwide insurance claims database, researchers conducted a retrospective cohort study to determine if early colonoscopy (colonoscopy within 24 hours) was correlated with reduced risk of rebleeding and hospital re-admission within 30 days. Patients with a primary diagnosis of diverticular bleeding who underwent inpatient colonoscopy were involved from January 2004 through September 2015. To determine the link between early colonoscopy and rebleeding or hospital re-admission within 30 days of discharge, multivariable logistic regression was performed. A total of 20,010 patients had diverticular bleeding colonoscopy; 11,690 patients had early colonoscopy. Findings suggested an association of early colonoscopy, endoscopic intervention, transfusion requirement, coronary artery disease, and chronic kidney disease with increased re-admission to the hospital within 30 days. Investigators linked early colonoscopy with increased risk of rebleeding events and hospital re-admissions in a propensity-matched analysis. These observations, however, may be caused by confounding factors.
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