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Dose–response relationship between body mass index and risks of all-cause mortality and disability among the elderly: A systematic review and meta-analysis

Clinical Nutrition Aug 01, 2018

Jiang M, et al. - Researchers explored the link between body mass index (BMI) and mortality and disability risks among the elderly via a systematic review and dose-response meta-analysis. For this investigation, they systematically searched PubMed, Embase, Cochrane library, and Google Scholar until December 2017 for studies reporting the hazard ratio and corresponding 95% confidence intervals of all-cause mortality or disability across different BMI categories. In this meta-analysis, 44 studies (37 studies on all-cause mortality and 9 studies on disability) were involved. Findings revealed that, among the elderly, the lower-end recommended BMI range (underweight) and obesity were related to significantly higher risks of mortality and disability. For the elderly group, the 23.0–28.0 BMI range could be the healthy weight range.

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