Do frailty measures improve prediction of mortality and morbidity following transcatheter aortic valve implantation? An analysis of the UK TAVI registry
BMJ Open Jul 04, 2018
Martin GP, et al. - Using data from the UK transcatheter aortic valve implantation (TAVI) registry, researchers examined if frailty was independently associated with TAVI outcomes and the predictive value of adding frailty into existing clinical prediction models (CPMs). Data from all patients who underwent a TAVI procedure in England or Wales between 2013 and 2014 were involved. Two thousand, six hundred twenty-four subjects were analyzed in this study. It was observed that frailty was linked with worse outcomes following TAVI, and including frailty metrics significantly improved the predictive performance of existing CPMs. Findings suggested that physician-estimated frailty/disability measures could aid TAVI risk stratification until more objective scales were routinely collected.
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