Lee SW, Shim SR, Jeong SY, et al. - Researchers sought to compare the performance of different preoperative imaging modalities for the localization of primary hyperparathyroidism (pHPT) by conducting a network meta-analysis. From the earliest possible indexing date until September 28, 2020, PubMed, Embase, and the Cochrane Library were searched. In total, 8,495 patients from 119 direct comparative studies using 2 or more imaging modalities for localization of pHPT were involved. According to the findings of this network meta-analysis, choline positron emission tomography and computed tomography (PET-CT) performed best in both patient-based and lesion-based analyses, implying that choline PET-CT would be the best preoperative imaging modality for pHPT localization.