Peyrony O, Chevret S, Meert AP, et al. - In this study, the benefit of direct ICU admission from the emergency department (ED) vs admission from wards was determined among patients with hematological malignancies requiring critical care. Researchers conducted a post hoc analysis stemmed from a prospective, multicenter cohort study of 1,011 critically ill adult patients with hematologic malignancies admitted to 17 ICU in Belgium and France from January 2010 to May 2011. Two hundred sixty-six (26.4%) cases were admitted directly to ICU from the ED; of these, 84 (31.6%) died in the hospital vs 311/742 (41.9%) in those who did not admit directly to ICU from the ED. After adjustment, a decreased in-hospital mortality was observed in correlation with direct ICU admission from the ED. Based on the finding, they suggest a higher likelihood to be alive at hospital discharge among patients with hematological malignancies admitted to the ICU if they were directly admitted from the ED rather than from the wards. They emphasize the importance of assessment of early predictors of poor outcomes in cancer patients admitted to the ED as it may enable early referral to the ICU and avoid delays in treatment initiation and misorientation.