Guo J, et al. – This analysis focused on the impact of the dimethyl–sulfoxide wet–bonding technique on composite–dentin bonds and to investigate its potential mechanism. The authors found that the 50% dimethyl sulfoxide (DMSO) pretreatment was useful in increasing the wettability of the etched dentin surface, promoting the penetration of the adhesive monomer, and enhancing the stability of the dentin collagen at the adhesive– dentin interface. All these changes might lead to higher quality dentin bonds, implying that DMSO wet bonding is a viable alternative to improve the durability of dentin bonding.