Hains I, et al. - This study involved the development, delivery, as well as evaluation of an educational program for general practitioners (GPs), addressing systematic management of patients with difficult-to-treat and severe asthma. The participants included over 1000 general practice health professionals. A survey was performed which was completed by 226 (25%) of 890 GPs who participated in the program. This program aided a greater proportion of GPs to recognize factors they would evaluate in cases with poor asthma control, especially for considering the risk of future adverse outcomes (+ 51%), changes in lifestyle (+ 38%), and self-management strategies (+ 35%). Post-participation, GPs gained a greater awareness of the biologic therapies that experts could think of prescribing to their patients with severe asthma (+ 75%), of the needs for a patient to be prescribed a biologic therapy (+ 73%), and that patients with distinct phenotypic features can respond differently to standard therapy (+ 67%). Overall, the benefits of an evidence-based educational program can include enhanced GP knowledge, confidence and intended practice in managing patients with difficult-to-treat and severe asthma.