Appelhof B, et al. - Researchers examined how young-onset dementia (YOD) and late-onset dementia (LOD) differ regarding neuropsychiatric symptoms (NPS) and if dementia subtype, gender, psychotropic drug use (PDU), or dementia severity contribute to these possible differences. They analyzed 386 nursing home residents with YOD and 350 with LOD and identified higher levels of apathy in NH residents with YOD. After adding the above listed characteristics to the multilevel modeling used to compare NPS between the groups, YOD displayed lower levels of verbally agitated behaviors. No differences in other NPS were found. YOD resulted in higher PDU rates, indicating a lower threshold for the use of PDU in the management of NPS. This emphasizes that, for the management of NPS in YOD, appropriate attention to non-pharmacological interventions is required.