He X, et al. - Researchers assessed colorectal cancer (CRC) risk in relation to the intake of total, cereal, fruit, and vegetable fiber, and whole grains. They also evaluated the links by tumor subsites and molecular markers. Participants included 90,869 women from the Nurses’ Health Study (1980-2012) and 47,924 men from the Health Professionals Follow-up Study (1986-2012). In men, a lower CRC risk was observed in relation to higher consumption of cereal fiber and whole grains, with a hazard ratio of 0.75 and 0.72, respectively. By tumor subsite or molecular markers, no heterogeneity was evident. Overall, they concluded that a substantial reduction of colorectal cancer risk is unlikely to be achieved with higher consumption of total dietary fiber within the range of a typical American diet.