Charisis S, Ntanasi E, Yannakoulia M, et al. - In this study, an elevated risk for incident dementia was observed in relation to higher diet inflammatory index (DII) scores (indicating greater proinflammatory diet potential) in community-dwelling older adults.

• From the Hellenic Longitudinal Investigation of Aging and Diet (HELIAD), a total of 1,059 individuals (mean age 73.1 years, 40.3% male, mean education 8.2 years) were included and were followed up for a mean of 3.05 (standard deviation 0.85) years.

• Of those, 62 developed incident dementia, and a 21% increase in the risk for dementia incidence (hazard ratio 1.21) was noted in relation to each additional unit of DII score.

• A 3 times more probability of developing incident dementia was observed in participants in the highest DII score tertile (maximal proinflammatory diet potential) vs those in the lowest one.

• A potential dose-response association was also indicated.