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Diastolic and systolic left ventricular dysfunction and mortality in chronic kidney disease patients on haemodialysis

Nephrology Aug 28, 2021

De Lima JJG, Macedo TA, Gowdak LHW, et al. - Findings demonstrate an independent link of both moderate–severe left ventricular diastolic dysfunction (LVDD) and LV systolic dysfunction (LVSD) with a higher likelihood of death and both exerted a similar influence on survival. A progressive link was noted between LVDD grades and mortality.

  • A retrospective study with 1,285 haemodialysis patients followed up until death or transplantation.

  • LVDD was split into 4 grades of severity.

  • A follow-up of 30 months revealed deaths of 419/1285 (33%) patients; 224 (53%) died because of CV events.

  • Occurrence of LVDD in 75% of patients was noted.

  • Prevalent diastolic abnormality was grade 1 DD.

  • The predominant form of moderate–severe DD was a pseudonormal pattern.

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