Klose-Jensen R, Therkildsen J, Blavnsfeldt ABG, et al. - This study was attempted to assess whether high-Resolution peripheral Quantitative Computed Tomography (HR-pQCT) of two metacarpophalangeal (MCP) joints can more accurately classify patients as having erosive rheumatoid arthritis (RA) compared with conventional radiography (CR) of 44 joints in the hands, wrists, and feet. Researchers designed a single-centre cross-sectional study investigating patients with established RA (disease duration ≥ 5 years) by HR-pQCT and CR. They further evaluated the second and third MCP joints of the dominant hand for erosions by HR-pQCT. A total of 353 individuals were enrolled, 66 (18.7%) patients were categorized as having non-erosive RA, and 287 (81.3%) had erosive RA by CR. The outcomes of this study indicated that the diagnostic accuracy of HR-pQCT scanning of only two MCP joints and conventional radiography of 44 joints suggest the two modalities were comparable for classifying patients with established RA as having an erosive disease.